Product record / Serums, madecassoside
SerumMediheal Madecassoside Blemish Repair Serum
- $17
- retail price
- $0.42
- per mL
- Data source
- Madecassoside is listed in the INCI (verified) alongside the full centelloid complex (Asiaticoside, Madecassic Acid, Asiatic Acid) plus niacinamide, panthenol, beta-glucan and ceramide NP; the do-more barrier/blemish serum Literal 'Madecassoside' verified genuinely present in the published INCI via INCIDecoder full ingredient list 2026-06-15. ASIN B0D62M93QY price PA-API-verified 2026-06-15.
- Best for
- Hydration
- How it feels
- Lightweight, fast-absorbing serum
- Value
- $17 for 40 mL · $0.42/mL
Bottom line A do-more cica serum — madecassoside plus the full centella complex, niacinamide and ceramides for calming and barrier support.
Editorial verdict / Social intelligence
A do-more cica serum — madecassoside plus the full centella complex, niacinamide and ceramides for calming and barrier support. 1
- Beauty benefit
- A soothing barrier serum built around madecassoside and the whole centella triterpene complex (asiaticoside, madecassic and asiatic acid), backed up with niacinamide, panthenol, beta-glucan and ceramide NP. It's the centella version of a do-it-all calming serum: settle redness, support the moisture barrier, and nudge a bit of tone with the niacinamide.
- Does it work
- Yes as a gentle, well-rounded soother for stressed, reactive or blemish-prone skin. Madecassoside and its sibling centelloids bring the calming, repair-supporting biology, while niacinamide and the barrier ingredients round it out — a sensible everyday serum to settle skin and support recovery. Honest framing: madecassoside is a soother-and-repair active, not a retinoid for wrinkles or a tyrosinase brightener for dark spots, and a lot of the underlying evidence is whole-extract or in-vitro, so think 'calm and support' rather than 'transform.' The niacinamide does the light tone work here, not the madecassoside. See the verified data below →
Consensus strength
ModerateMadecassoside has well-documented soothing, wound-healing, collagen-supporting and antioxidant biology and is the marker triterpene behind centella/cica products — but much of the strongest evidence is in-vitro, animal, oral or whole-extract, and human facial trials test soothing blends rather than isolated madecassoside. A gentle, well-tolerated soother-and-repair active that genuinely calms and supports skin, not a retinoid-level anti-ager or a tyrosinase brightener; potency varies with how the centella extract is standardized.
01 / The key active
madecassoside
madecassoside is present in the formula; the brand does not disclose the exact concentration.
Madecassoside is listed in the INCI (verified) alongside the full centelloid complex (Asiaticoside, Madecassic Acid, Asiatic Acid) plus niacinamide, panthenol, beta-glucan and ceramide NP; the do-more barrier/blemish serum. Literal 'Madecassoside' verified genuinely present in the published INCI via INCIDecoder full ingredient list 2026-06-15. ASIN B0D62M93QY price PA-API-verified 2026-06-15.
Other products with madecassoside:
02 / The full ingredient list
Every ingredient, in label order
Exactly as printed, each token matched to the EU CosIng register and flagged where a CIR safety assessment exists. Highlighted rows are the key actives.
| # | Ingredient, as printed | CosIng functions | CIR |
|---|---|---|---|
| 01 | Water |
| — |
| 02 | Glycerin |
| ✓ reviewed |
| 03 | Butylene Glycol |
| ✓ reviewed |
| 04 | Propanediol |
| ✓ reviewed |
| 05 | 1,2-Hexanediol |
| ✓ reviewed |
| 06 | Niacinamide |
| ✓ reviewed |
| 07 | Glyceryl Polymethacrylate |
| ✓ reviewed |
| 08 | Panthenol |
| ✓ reviewed |
| 09 | Betaine |
| ✓ reviewed |
| 10 | Polyglyceryl-10 Laurate |
| ✓ reviewed |
| 11 | Acrylates/C10-30 Alkyl Acrylate Crosspolymer |
| ✓ reviewed |
| 12 | Diphenyl Dimethicone |
| ✓ reviewed |
| 13 | Triethylhexanoin |
| ✓ reviewed |
| 14 | Tromethamine |
| ✓ reviewed |
| 15 | Madecassoside |
| — |
| 16 | Ethylhexylglycerin |
| ✓ reviewed |
| 17 | Hydrogenated Lecithin |
| ✓ reviewed |
| 18 | Xanthan Gum |
| ✓ reviewed |
| 19 | Sodium Hyaluronate |
| ✓ reviewed |
| 20 | Centella Asiatica Extract |
| ✓ reviewed |
| 21 | Asiaticoside |
| — |
| 22 | Beta-Glucan |
| ✓ reviewed |
| 23 | Madecassic Acid |
| — |
| 24 | Asiatic Acid |
| — |
| 25 | Ceramide NP |
| ✓ reviewed |
| 26 | Tocopherol |
| ✓ reviewed |
26 ingredients as printed · 26 exact CosIng matches · source: madecassoside is listed in the inci (verified) alongside the full centelloid complex (asiaticoside, madecassic acid, asiatic acid) plus niacinamide, panthenol, beta-glucan and ceramide np; the do-more barrier/blemish serum
03 / Where to buy
Where to buy Madecassoside Blemish Repair Serum
Some links on this page earn us a commission. It never changes our analysis — the methodology is public.
04 / What people say
What buyers actually say
What works
- Common The star cica triterpene — genuine soothing, wound-healing and antioxidant biology behind centella's calm-and-repair reputation 62
It has well established wound healing, skin-soothing and antioxidant activities. Editorial
-
Used at 0.2%, Madecassoside reduces redness and peeling in skin with light atopic dermatitis as well as itching in psoriasis-prone skin. Editorial
What to know
What you'd only know from the reviews
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This is one of the more complete 'cica' serums because it isn't just centella extract — the label actually lists madecassoside and the other three centelloids individually, plus barrier helpers like ceramide NP and beta-glucan. That's a good sign you're getting the real triterpenes rather than a token splash of plant extract, though no brand discloses exactly how much madecassoside is inside. 4
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05 / Questions
Frequently asked
- What's in Mediheal Madecassoside Blemish Repair Serum?
- Mediheal Madecassoside Blemish Repair Serum lists 26 ingredients. Key active: madecassoside (concentration undisclosed). Literal 'Madecassoside' verified genuinely present in the published INCI via INCIDecoder full ingredient list 2026-06-15. ASIN B0D62M93QY price PA-API-verified 2026-06-15. The full ingredient list, matched to EU CosIng, is on this page.
- Does Mediheal Madecassoside Blemish Repair Serum work?
- Yes as a gentle, well-rounded soother for stressed, reactive or blemish-prone skin. Madecassoside and its sibling centelloids bring the calming, repair-supporting biology, while niacinamide and the barrier ingredients round it out — a sensible everyday serum to settle skin and support recovery. Honest framing: madecassoside is a soother-and-repair active, not a retinoid for wrinkles or a tyrosinase brightener for dark spots, and a lot of the underlying evidence is whole-extract or in-vitro, so think 'calm and support' rather than 'transform.' The niacinamide does the light tone work here, not the madecassoside.
- How much madecassoside is in Mediheal Madecassoside Blemish Repair Serum?
- Mediheal does not publicly disclose the exact concentration. madecassoside appears in the INCI list; the amount is undisclosed. Literal 'Madecassoside' verified genuinely present in the published INCI via INCIDecoder full ingredient list 2026-06-15. ASIN B0D62M93QY price PA-API-verified 2026-06-15.
- Where can I buy Mediheal Madecassoside Blemish Repair Serum?
- $17.00 on Amazon (price recorded as of the date shown). Literal 'Madecassoside' verified genuinely present in the published INCI via INCIDecoder full ingredient list 2026-06-15. ASIN B0D62M93QY price PA-API-verified 2026-06-15.