Verified Beauty Data

Product record / Moisturizers, madecassoside

Moisturizer

A'PIEU Madecassoside Cream 2X

Moisturizer · 50 mL · centella asiatica leaf water base with madecassoside and the full centelloid complex listed in the inci (verified); a richer, silicone-cushioned soothing cream ('2x' madecassoside vs the original)

$24.72
retail price
$0.49
per mL
Data source
Centella Asiatica Leaf Water base with Madecassoside and the full centelloid complex listed in the INCI (verified); a richer, silicone-cushioned soothing cream ('2x' madecassoside vs the original) Literal 'Madecassoside' verified genuinely present in the published INCI via INCIDecoder full ingredient list 2026-06-15. ASIN B08XY9WDJ6 price PA-API-verified 2026-06-15.
A'PIEU Madecassoside Cream 2X bottle
Pictured: Amazon listing
Best for
Hydration
How it feels
Moisturizer
Value
$24.72 for 50 mL · $0.49/mL

Bottom line A richer cica moisturizer built on centella water and a double dose of madecassoside — a cushiony daily soother.

Editorial verdict / Social intelligence

Qualified yes Product review

A richer cica moisturizer built on centella water and a double dose of madecassoside — a cushiony daily soother. 1

Beauty benefit
A soothing cream whose very first ingredient is Centella Asiatica leaf water, with madecassoside and the full centelloid complex listed further down and a silicone-cushioned, velvety finish. The '2X' refers to a doubled madecassoside level versus the original — it's the comfortable, moisturizing way to get cica into a routine.
Does it work
Yes as a gentle daily moisturizer for skin that wants calming and cushioning. The centella water and triterpenes do the soothing-and-support work, while the silicone-rich base gives a smooth, blurred feel some people love and others find too 'slip-y'. Honest framing: it's a soother and barrier-supporter, not a treatment — madecassoside isn't a retinoid or a brightener, and the cream's job is comfort and calm, not resurfacing or fading spots. A solid pick if you want cica in moisturizer form rather than a serum. See the verified data below →

Consensus strength

Moderate

Madecassoside has well-documented soothing, wound-healing, collagen-supporting and antioxidant biology and is the marker triterpene behind centella/cica products — but much of the strongest evidence is in-vitro, animal, oral or whole-extract, and human facial trials test soothing blends rather than isolated madecassoside. A gentle, well-tolerated soother-and-repair active that genuinely calms and supports skin, not a retinoid-level anti-ager or a tyrosinase brightener; potency varies with how the centella extract is standardized.

01 / The key active

madecassoside

madecassoside is present in the formula; the brand does not disclose the exact concentration.

Primary active

madecassoside

Concentration undisclosed

Read the madecassoside dossier →

Centella Asiatica Leaf Water base with Madecassoside and the full centelloid complex listed in the INCI (verified); a richer, silicone-cushioned soothing cream ('2x' madecassoside vs the original). Literal 'Madecassoside' verified genuinely present in the published INCI via INCIDecoder full ingredient list 2026-06-15. ASIN B08XY9WDJ6 price PA-API-verified 2026-06-15.

02 / The full ingredient list

Every ingredient, in label order

Exactly as printed, each token matched to the EU CosIng register and flagged where a CIR safety assessment exists. Highlighted rows are the key actives.

# Ingredient, as printed CosIng functions CIR
01 Centella Asiatica Leaf Water
  • skin conditioning
✓ reviewed
02 Cyclopentasiloxane
  • skin conditioning - emollient
  • hair conditioning
  • skin conditioning
  • solvent
✓ reviewed
03 Water
  • antiplaque
  • skin conditioning
  • solvent
04 Glycerin
  • denaturant
  • hair conditioning
  • humectant
  • oral care
  • skin protecting
  • solvent
  • viscosity controlling
  • perfuming
  • fragrance
  • skin conditioning - humectant
✓ reviewed
05 Phenyl Trimethicone
  • antifoaming
  • hair conditioning
  • skin conditioning - occlusive
✓ reviewed
06 Propanediol
  • solvent
  • viscosity controlling
✓ reviewed
07 PEG-10 Dimethicone
  • hair conditioning
  • skin conditioning
✓ reviewed
08 Cyclohexasiloxane
  • skin conditioning - emollient
  • hair conditioning
  • solvent
✓ reviewed
09 Niacinamide
  • smoothing
✓ reviewed
10 Pentylene Glycol
  • skin conditioning
  • solvent
✓ reviewed
11 1,2-Hexanediol
  • skin conditioning
  • solvent
✓ reviewed
12 Disteardimonium Hectorite
  • light stabilizer
  • viscosity controlling
✓ reviewed
13 Sodium Chloride
  • bulking
  • fragrance
  • oral care
  • viscosity controlling
14 Hydroxyacetophenone
  • antioxidant
✓ reviewed
15 Madecassoside
  • antioxidant
  • skin conditioning
16 Dimethicone Crosspolymer
  • emulsion stabilising
  • hair fixing
  • viscosity controlling
✓ reviewed
17 Adenosine
  • skin conditioning
✓ reviewed
18 Asiaticoside
  • antioxidant
  • skin conditioning
  • perfuming
19 Centella Asiatica Leaf Extract
  • skin conditioning
✓ reviewed
20 Madecassic Acid
  • skin conditioning
21 Asiatic Acid
  • skin conditioning
  • light stabilizer
22 Centella Asiatica Extract
  • cleansing
  • skin conditioning
  • smoothing
  • soothing
  • tonic
✓ reviewed

22 ingredients as printed · 22 exact CosIng matches · source: centella asiatica leaf water base with madecassoside and the full centelloid complex listed in the inci (verified); a richer, silicone-cushioned soothing cream ('2x' madecassoside vs the original)

03 / Where to buy

Where to buy Madecassoside Cream 2X

Buy on Amazon $24.72

Some links on this page earn us a commission. It never changes our analysis — the methodology is public.

04 / What people say

What buyers actually say

What works

  • Common The star cica triterpene — genuine soothing, wound-healing and antioxidant biology behind centella's calm-and-repair reputation 62
    It has well established wound healing, skin-soothing and antioxidant activities. Editorial
  • Common A gentle, well-tolerated soother that also supports hydration and the barrier 63
    Used at 0.2%, Madecassoside reduces redness and peeling in skin with light atopic dermatitis as well as itching in psoriasis-prone skin. Editorial

What to know

  • Common A soother-and-repair active, not a retinoid or a brightener — and much of the evidence is whole-centella/in-vitro with the proof still being built 15
    considered cosmetically beneficial for their role in anti-ageing, skin hydration, collagen synthesis, UV protection and curing scars review

What you'd only know from the reviews

  • The label order tells the honest story: centella leaf water leads, and madecassoside plus the other centelloids are genuinely listed (not just generic 'centella extract'), so you're getting the real triterpenes. The trade-off is texture — this is a silicone-cushioned cream, so it feels smooth and blurring but won't suit everyone who dislikes that slip. 6

  1. 1 review Therapeutic properties and pharmacological activities of asiaticoside and madecassoside: A review 2023
  2. 2 Study Madecassoside isolated from Centella asiatica facilitates burn wound healing in mice 2008
  3. 3 Study Split-face RCT of a soothing facial mask (incl. madecassoside) post-photorejuvenation 2025
  4. 4 Study Comparative activity of asiaticoside and madecassoside on type I and III collagen synthesis 1995
  5. 5 Study Burn wound healing properties of asiaticoside and madecassoside 2016
  6. 6 Editorial Madecassoside — INCIDecoder 2026

05 / Questions

Frequently asked

What's in A'PIEU Madecassoside Cream 2X?
A'PIEU Madecassoside Cream 2X lists 22 ingredients. Key active: madecassoside (concentration undisclosed). Literal 'Madecassoside' verified genuinely present in the published INCI via INCIDecoder full ingredient list 2026-06-15. ASIN B08XY9WDJ6 price PA-API-verified 2026-06-15. The full ingredient list, matched to EU CosIng, is on this page.
Does A'PIEU Madecassoside Cream 2X work?
Yes as a gentle daily moisturizer for skin that wants calming and cushioning. The centella water and triterpenes do the soothing-and-support work, while the silicone-rich base gives a smooth, blurred feel some people love and others find too 'slip-y'. Honest framing: it's a soother and barrier-supporter, not a treatment — madecassoside isn't a retinoid or a brightener, and the cream's job is comfort and calm, not resurfacing or fading spots. A solid pick if you want cica in moisturizer form rather than a serum.
How much madecassoside is in A'PIEU Madecassoside Cream 2X?
A'PIEU does not publicly disclose the exact concentration. madecassoside appears in the INCI list; the amount is undisclosed. Literal 'Madecassoside' verified genuinely present in the published INCI via INCIDecoder full ingredient list 2026-06-15. ASIN B08XY9WDJ6 price PA-API-verified 2026-06-15.
Where can I buy A'PIEU Madecassoside Cream 2X?
$24.72 on Amazon (price recorded as of the date shown). Literal 'Madecassoside' verified genuinely present in the published INCI via INCIDecoder full ingredient list 2026-06-15. ASIN B08XY9WDJ6 price PA-API-verified 2026-06-15.