Verified Beauty Data

Product record / Moisturizers, madecassoside

Moisturizer

A'PIEU Madecassoside Tetrasome Cica Cream

Moisturizer · 50 mL · a lighter, ferment-rich cica gel-cream with madecassoside and the centelloid complex listed in the inci (verified) plus panthenol; the budget, lightweight option

$16
retail price
$0.32
per mL
Data source
A lighter, ferment-rich cica gel-cream with Madecassoside and the centelloid complex listed in the INCI (verified) plus panthenol; the budget, lightweight option Literal 'Madecassoside' verified genuinely present in the published INCI via INCIDecoder full ingredient list 2026-06-15. ASIN B0CJDTJWFG price PA-API-verified 2026-06-15.
A'PIEU Madecassoside Tetrasome Cica Cream bottle
Pictured: Amazon listing
Best for
Hydration
How it feels
Moisturizer
Value
$16 for 50 mL · $0.32/mL

Bottom line The lightweight, budget cica cream — a fast-absorbing gel-cream with madecassoside, ferments and panthenol.

Editorial verdict / Social intelligence

Qualified yes Product review

The lightweight, budget cica cream — a fast-absorbing gel-cream with madecassoside, ferments and panthenol. 1

Beauty benefit
A lighter 'tetrasome' cica gel-cream: water-based, fast-absorbing, with niacinamide, panthenol, fermented soothing extracts and the centella triterpenes (madecassoside, asiaticoside, madecassic and asiatic acid) listed on the label. It's the cheaper, less-occlusive way to get cica calming without a heavy cream feel.
Does it work
Yes as an easy, affordable daily soother — especially for combination or oilier skin that finds richer cica creams too heavy. The fermented extracts and panthenol add a hydrating, calming layer alongside the centella triterpenes, and the gel-cream texture sinks in fast. Honest framing: like all cica, madecassoside here is a gentle soother-and-repair active, not a retinoid or a brightener, and the centella sits lower on the ingredient list, so set expectations on comfort and calm rather than active treatment. Great value for a lightweight everyday calming cream. See the verified data below →

Consensus strength

Moderate

Madecassoside has well-documented soothing, wound-healing, collagen-supporting and antioxidant biology and is the marker triterpene behind centella/cica products — but much of the strongest evidence is in-vitro, animal, oral or whole-extract, and human facial trials test soothing blends rather than isolated madecassoside. A gentle, well-tolerated soother-and-repair active that genuinely calms and supports skin, not a retinoid-level anti-ager or a tyrosinase brightener; potency varies with how the centella extract is standardized.

01 / The key active

madecassoside

madecassoside is present in the formula; the brand does not disclose the exact concentration.

Primary active

madecassoside

Concentration undisclosed

Read the madecassoside dossier →

A lighter, ferment-rich cica gel-cream with Madecassoside and the centelloid complex listed in the INCI (verified) plus panthenol; the budget, lightweight option. Literal 'Madecassoside' verified genuinely present in the published INCI via INCIDecoder full ingredient list 2026-06-15. ASIN B0CJDTJWFG price PA-API-verified 2026-06-15.

02 / The full ingredient list

Every ingredient, in label order

Exactly as printed, each token matched to the EU CosIng register and flagged where a CIR safety assessment exists. Highlighted rows are the key actives.

# Ingredient, as printed CosIng functions CIR
01 Water
  • antiplaque
  • skin conditioning
  • solvent
02 Butylene Glycol
  • humectant
  • fragrance
  • skin conditioning
  • solvent
  • viscosity controlling
✓ reviewed
03 Caprylyl Methicone
  • skin conditioning
✓ reviewed
04 Niacinamide
  • smoothing
✓ reviewed
05 Silica
  • abrasive
  • absorbent
  • anticaking
  • bulking
  • opacifying
  • viscosity controlling
✓ reviewed
06 1,2-Hexanediol
  • skin conditioning
  • solvent
✓ reviewed
07 Panthenol
  • antistatic
  • hair conditioning
  • skin conditioning
✓ reviewed
08 Glycerin
  • denaturant
  • hair conditioning
  • humectant
  • oral care
  • skin protecting
  • solvent
  • viscosity controlling
  • perfuming
  • fragrance
  • skin conditioning - humectant
✓ reviewed
09 Pentylene Glycol
  • skin conditioning
  • solvent
✓ reviewed
10 Centella Asiatica Leaf Extract
  • skin conditioning
✓ reviewed
11 Lactobacillus Ferment Lysate
  • skin conditioning
✓ reviewed
12 Caprylic/Capric Triglyceride
  • fragrance
  • solvent
  • perfuming
  • skin conditioning - occlusive
✓ reviewed
13 Tromethamine
  • buffering
  • fragrance
✓ reviewed
14 Hydrogenated Lecithin
  • surfactant - emulsifying
  • skin conditioning
✓ reviewed
15 Ethylhexylglycerin
  • deodorant
  • skin conditioning
✓ reviewed
16 Madecassoside
  • antioxidant
  • skin conditioning
17 Dipotassium Glycyrrhizate
  • humectant
  • skin conditioning
✓ reviewed
18 Adenosine
  • skin conditioning
✓ reviewed
19 Tocopherol
  • antioxidant
  • fragrance
  • skin conditioning - miscellaneous
  • skin conditioning - occlusive
✓ reviewed
20 Asiaticoside
  • antioxidant
  • skin conditioning
  • perfuming
21 Madecassic Acid
  • skin conditioning
22 Asiatic Acid
  • skin conditioning
  • light stabilizer
23 Xanthan Gum
  • binding
  • surfactant - emulsifying
  • emulsion stabilising
  • gel forming
  • skin conditioning
  • surfactant - cleansing
  • viscosity controlling
✓ reviewed

23 ingredients as printed · 23 exact CosIng matches · source: a lighter, ferment-rich cica gel-cream with madecassoside and the centelloid complex listed in the inci (verified) plus panthenol; the budget, lightweight option

03 / Where to buy

Where to buy Madecassoside Tetrasome Cica Cream

Buy on Amazon $16

Some links on this page earn us a commission. It never changes our analysis — the methodology is public.

04 / What people say

What buyers actually say

What works

  • Common The star cica triterpene — genuine soothing, wound-healing and antioxidant biology behind centella's calm-and-repair reputation 62
    It has well established wound healing, skin-soothing and antioxidant activities. Editorial
  • Common A gentle, well-tolerated soother that also supports hydration and the barrier 63
    Used at 0.2%, Madecassoside reduces redness and peeling in skin with light atopic dermatitis as well as itching in psoriasis-prone skin. Editorial

What to know

  • Common A soother-and-repair active, not a retinoid or a brightener — and much of the evidence is whole-centella/in-vitro with the proof still being built 15
    considered cosmetically beneficial for their role in anti-ageing, skin hydration, collagen synthesis, UV protection and curing scars review

What you'd only know from the reviews

  • At around sixteen dollars this is the value pick of the three, and the lighter gel-cream texture makes it the friendliest for oilier or combination skin. The centelloids sit further down the list than in a dedicated serum, so treat it as a pleasant everyday soothing moisturizer rather than a concentrated madecassoside treatment. 3

  1. 1 review Therapeutic properties and pharmacological activities of asiaticoside and madecassoside: A review 2023
  2. 2 Study Madecassoside isolated from Centella asiatica facilitates burn wound healing in mice 2008
  3. 3 Study Split-face RCT of a soothing facial mask (incl. madecassoside) post-photorejuvenation 2025
  4. 4 Study Comparative activity of asiaticoside and madecassoside on type I and III collagen synthesis 1995
  5. 5 Study Burn wound healing properties of asiaticoside and madecassoside 2016
  6. 6 Editorial Madecassoside — INCIDecoder 2026

05 / Questions

Frequently asked

What's in A'PIEU Madecassoside Tetrasome Cica Cream?
A'PIEU Madecassoside Tetrasome Cica Cream lists 23 ingredients. Key active: madecassoside (concentration undisclosed). Literal 'Madecassoside' verified genuinely present in the published INCI via INCIDecoder full ingredient list 2026-06-15. ASIN B0CJDTJWFG price PA-API-verified 2026-06-15. The full ingredient list, matched to EU CosIng, is on this page.
Does A'PIEU Madecassoside Tetrasome Cica Cream work?
Yes as an easy, affordable daily soother — especially for combination or oilier skin that finds richer cica creams too heavy. The fermented extracts and panthenol add a hydrating, calming layer alongside the centella triterpenes, and the gel-cream texture sinks in fast. Honest framing: like all cica, madecassoside here is a gentle soother-and-repair active, not a retinoid or a brightener, and the centella sits lower on the ingredient list, so set expectations on comfort and calm rather than active treatment. Great value for a lightweight everyday calming cream.
How much madecassoside is in A'PIEU Madecassoside Tetrasome Cica Cream?
A'PIEU does not publicly disclose the exact concentration. madecassoside appears in the INCI list; the amount is undisclosed. Literal 'Madecassoside' verified genuinely present in the published INCI via INCIDecoder full ingredient list 2026-06-15. ASIN B0CJDTJWFG price PA-API-verified 2026-06-15.
Where can I buy A'PIEU Madecassoside Tetrasome Cica Cream?
$16.00 on Amazon (price recorded as of the date shown). Literal 'Madecassoside' verified genuinely present in the published INCI via INCIDecoder full ingredient list 2026-06-15. ASIN B0CJDTJWFG price PA-API-verified 2026-06-15.