Verified Beauty Data

Product record / Serums, polynucleotides-pdrn

Serum

medicube PDRN Pink Peptide Serum with Salmon DNA

Serum · sodium dna (pdrn) disclosed in inci; concentration undisclosed

$18.90
retail price
Data source
Sodium DNA (PDRN) disclosed in INCI; concentration undisclosed Sodium DNA present in INCI (INCIDecoder-verified, position 5); ASIN B0DBF65JYY price PA-API-verified 2026-06-14. Topical serum, not the clinical injectable.
medicube PDRN Pink Peptide Serum with Salmon DNA bottle
Pictured: Amazon listing
Best for
Hydration · Anti-aging & firmness
How it feels
Lightweight, fast-absorbing serum
Value
$18.90

Bottom line A topical 'salmon DNA' (PDRN) serum that pairs Sodium DNA with copper and palmitoyl peptides for hydration and a smoother, plumped look — popular and gentle, but a serum, not the injectable.

Editorial verdict / Social intelligence

Qualified yes Product review

A topical 'salmon DNA' (PDRN) serum that pairs Sodium DNA with copper and palmitoyl peptides for hydration and a smoother, plumped look — popular and gentle, but a serum, not the injectable. 1

Beauty benefit
A peptide-forward 'pink' serum that combines Sodium DNA (the cosmetic INCI for PDRN / salmon DNA) with niacinamide, hydrolyzed collagen, copper tripeptide and several palmitoyl peptides for hydration and a smoother, plumped appearance.
Does it work
Honestly: this is a topical, not the clinical injectable. PDRN's strong evidence is for in-dermis 'skin booster' injection; here Sodium DNA sits fifth on the list among many peptides and humectants in a leave-on serum, where a large DNA polymer's penetration is unproven. Expect a pleasant, hydrating, peptide-supported serum — not the results of an injectable PDRN treatment. See the verified data below →

Consensus strength

Moderate

PDRN has strong evidence as an INJECTED 'skin booster'; these are topical serums where Sodium DNA (the cosmetic INCI for PDRN) is one of many actives, and topical penetration of a large DNA biopolymer is unproven — judge them as pleasant peptide-and-hydration serums, not as the clinical injectable.

01 / The key active

polynucleotides-pdrn

polynucleotides-pdrn is present in the formula; the brand does not disclose the exact concentration.

Primary active

polynucleotides-pdrn

Concentration undisclosed

Read the polynucleotides-pdrn dossier →

Sodium DNA (PDRN) disclosed in INCI; concentration undisclosed. Sodium DNA present in INCI (INCIDecoder-verified, position 5); ASIN B0DBF65JYY price PA-API-verified 2026-06-14. Topical serum, not the clinical injectable.

Other products with polynucleotides-pdrn:

02 / The full ingredient list

Every ingredient, in label order

Exactly as printed, each token matched to the EU CosIng register and flagged where a CIR safety assessment exists. Highlighted rows are the key actives.

# Ingredient, as printed CosIng functions CIR
01 Water
  • antiplaque
  • skin conditioning
  • solvent
02 Disodium EDTA
  • chelating
  • viscosity controlling
✓ reviewed
03 Niacinamide
  • smoothing
✓ reviewed
04 Hydrolyzed Collagen
  • antistatic
  • skin conditioning - emollient
  • film forming
  • hair conditioning
  • humectant
  • skin conditioning
✓ reviewed
05 Sodium DNA
  • skin conditioning
06 Millet Extract no CosIng function record
07 Copper Tripeptide-1
  • skin conditioning
✓ reviewed
08 Acetyl Hexapeptide-8
  • humectant
  • skin conditioning
✓ reviewed
09 Palmitoyl Pentapeptide-4
  • skin conditioning
✓ reviewed
10 Palmitoyl Tripeptide-1
  • skin conditioning
✓ reviewed
11 Palmitoyl Tetrapeptide-7
  • skin conditioning - miscellaneous
✓ reviewed
12 Butylene Glycol
  • humectant
  • fragrance
  • skin conditioning
  • solvent
  • viscosity controlling
✓ reviewed
13 1,2-Hexanediol
  • skin conditioning
  • solvent
✓ reviewed
14 Glycerin
  • denaturant
  • hair conditioning
  • humectant
  • oral care
  • skin protecting
  • solvent
  • viscosity controlling
  • perfuming
  • fragrance
  • skin conditioning - humectant
✓ reviewed
15 Dipropylene Glycol
  • fragrance
  • solvent
  • viscosity controlling
  • perfuming
✓ reviewed
16 Polyglycerin-3
  • humectant
✓ reviewed
17 Glyceryl Acrylate/Acrylic Acid Copolymer
  • humectant
  • viscosity controlling
✓ reviewed
18 PVM/MA Copolymer
  • antistatic
  • binding
  • emulsion stabilising
  • film forming
  • hair fixing
  • viscosity controlling
✓ reviewed
19 Sodium Hyaluronate
  • humectant
  • skin conditioning
✓ reviewed
20 Ethylhexylglycerin
  • deodorant
  • skin conditioning
✓ reviewed
21 Glycereth-26
  • humectant
  • viscosity controlling
✓ reviewed
22 Adenosine
  • skin conditioning
✓ reviewed
23 Acrylates/C10-30 Alkyl Acrylate Crosspolymer
  • emulsion stabilising
  • film forming
  • viscosity controlling
✓ reviewed
24 Isopropyl Myristate
  • binding
  • skin conditioning - emollient
  • fragrance
  • perfuming
✓ reviewed
25 Ubiquinone
  • antioxidant
  • skin conditioning
✓ reviewed
26 Fragrance no CosIng function record
27 Caprylyl Glycol
  • deodorant
  • skin conditioning - emollient
  • hair conditioning
  • skin conditioning
✓ reviewed
28 Tromethamine
  • buffering
  • fragrance
✓ reviewed
29 Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
  • anticaking
  • emulsion stabilising
  • film forming
  • opacifying
  • viscosity controlling
✓ reviewed
30 Polyisobutene
  • binding
  • film forming
  • viscosity controlling
✓ reviewed
31 Caprylyl/Capryl Glucoside
  • cleansing
  • foaming
  • surfactant - cleansing
✓ reviewed
32 Sorbitan Oleate
  • surfactant - emulsifying
✓ reviewed
33 Atelocollagen
  • skin conditioning
✓ reviewed
34 Salmon Egg Extract
  • not reported
35 Cyanocobalamin
  • skin conditioning
36 Melia Azadirachta Leaf Extract
  • skin conditioning
37 Melia Azadirachta Flower Extract
  • skin conditioning
38 Curcuma Longa (Turmeric) Root Extract
  • fragrance
  • perfuming
39 Ocimum Sanctum Leaf Extract
  • skin conditioning
40 Corallina Officinalis Extract
  • skin conditioning
✓ reviewed

40 ingredients as printed · 40 exact CosIng matches · source: sodium dna (pdrn) disclosed in inci; concentration undisclosed

03 / Where to buy

Where to buy PDRN Pink Peptide Serum with Salmon DNA

Buy on Amazon $18.90

Some links on this page earn us a commission. It never changes our analysis — the methodology is public.

04 / What people say

What buyers actually say

What works

  • Common Hydrating, plumping peptide-and-PDRN serum with a regenerative-leaning active blend 23
    The low-molecular-weight fraction (Low-Peony PDRN) markedly enhanced skin cell proliferation and migration, upregulated extracellular matrix-related genes (COL1A1, COL5A1, ELN, and FBN1) Study
  • Common PDRN has a real regenerative mechanism (adenosine A2A receptor) behind the trend 16
    Polydeoxyribonucleotide (PDRN), a compound having a mixture of deoxyribonucleotide polymers, stimulates the A2 purinergic receptor with no toxic or adverse effect. Study

What to know

  • Common This is a TOPICAL serum, not the clinical injectable — PDRN's strong evidence is for in-dermis injection, and topical penetration of a large DNA polymer is unproven 45
    Polydeoxyribonucleotide (PDRN) has the ability to regenerate skin cells and improve the skin barrier and wound healing. Study

What you'd only know from the reviews

  • 'Salmon DNA' on the front of the box is 'Sodium DNA' in the INCI — the cosmetic form of PDRN. It's a genuine inclusion, but it's one active among a dozen peptides and collagens here, so this is really a peptide serum with PDRN, not a PDRN treatment. 3

  1. 1 Study PDRN stimulates the adenosine A2A receptor — angiogenesis & wound healing (mechanism) 2008
  2. 2 Study Low-MW PDRN enhances proliferation/migration + ECM genes (in vitro) 2025
  3. 3 review PDRN/PN in gels, creams, serums, masks AND injectables — definitions/applications 2025
  4. 4 Study Plant-derived PDRN regenerates skin cells & improves barrier (in vitro / topical lane) 2023
  5. 5 Study Intradermal long-chain PN filler — effective injectable skin rejuvenation 2016
  6. 6 review PDRN improves wound healing (local & systemic) — regenerative platform 2021

05 / Questions

Frequently asked

What's in medicube PDRN Pink Peptide Serum with Salmon DNA?
medicube PDRN Pink Peptide Serum with Salmon DNA lists 40 ingredients. Key active: polynucleotides-pdrn (concentration undisclosed). Sodium DNA present in INCI (INCIDecoder-verified, position 5); ASIN B0DBF65JYY price PA-API-verified 2026-06-14. Topical serum, not the clinical injectable. The full ingredient list, matched to EU CosIng, is on this page.
Does medicube PDRN Pink Peptide Serum with Salmon DNA work?
Honestly: this is a topical, not the clinical injectable. PDRN's strong evidence is for in-dermis 'skin booster' injection; here Sodium DNA sits fifth on the list among many peptides and humectants in a leave-on serum, where a large DNA polymer's penetration is unproven. Expect a pleasant, hydrating, peptide-supported serum — not the results of an injectable PDRN treatment.
How much polynucleotides-pdrn is in medicube PDRN Pink Peptide Serum with Salmon DNA?
medicube does not publicly disclose the exact concentration. polynucleotides-pdrn appears in the INCI list; the amount is undisclosed. Sodium DNA present in INCI (INCIDecoder-verified, position 5); ASIN B0DBF65JYY price PA-API-verified 2026-06-14. Topical serum, not the clinical injectable.
Where can I buy medicube PDRN Pink Peptide Serum with Salmon DNA?
$18.90 on Amazon (price recorded as of the date shown). Sodium DNA present in INCI (INCIDecoder-verified, position 5); ASIN B0DBF65JYY price PA-API-verified 2026-06-14. Topical serum, not the clinical injectable.