{
 "dataset": "retinaldehyde-trials",
 "source": "https://verifiedbeautydata.com/ingredients/retinaldehyde/",
 "licence": "CC BY 4.0 — https://creativecommons.org/licenses/by/4.0/",
 "cite_as": "Verified Beauty Data, \"retinaldehyde: trials table\", https://verifiedbeautydata.com/data/gold/retinaldehyde-trials.json",
 "row_count": 7,
 "rows": [
  {
   "trial": "Griffiths 1995; Kwon 2018",
   "arm": "0.025% tretinoin",
   "outcome": "Tretinoin: epidermal thickening at 48 weeks (Griffiths 1995)",
   "value_pct": 28,
   "n": 139,
   "duration_weeks": 48,
   "url": "https://pubmed.ncbi.nlm.nih.gov/7544967/"
  },
  {
   "trial": "Griffiths 1995; Kwon 2018",
   "arm": "0.1% tretinoin",
   "outcome": "Tretinoin: epidermal thickening at 48 weeks (Griffiths 1995)",
   "value_pct": 30,
   "n": 139,
   "duration_weeks": 48,
   "url": "https://pubmed.ncbi.nlm.nih.gov/7544967/"
  },
  {
   "trial": "Griffiths 1995; Kwon 2018",
   "arm": "0.05% retinaldehyde",
   "outcome": "Retinal: overall photoaging improvement at 12 weeks (Kwon 2018)",
   "value_pct": 95,
   "n": 139,
   "duration_weeks": 48,
   "url": "https://pubmed.ncbi.nlm.nih.gov/7544967/"
  },
  {
   "trial": "Griffiths 1995; Kwon 2018",
   "arm": "0.1% retinaldehyde",
   "outcome": "Retinal: overall photoaging improvement at 12 weeks (Kwon 2018)",
   "value_pct": 95,
   "n": 139,
   "duration_weeks": 48,
   "url": "https://pubmed.ncbi.nlm.nih.gov/7544967/"
  },
  {
   "trial": "Shalita 1996 (PMID 8609263)",
   "arm": "adapalene 0.1% gel",
   "outcome": "total lesion count reduction",
   "value_pct": 49,
   "n": null,
   "duration_weeks": 12,
   "url": "https://pubmed.ncbi.nlm.nih.gov/8609263/"
  },
  {
   "trial": "Weinstein 1991 (PMID 2024983)",
   "arm": "tretinoin 0.05%",
   "outcome": "subjects with overall improvement",
   "value_pct": 79,
   "n": null,
   "duration_weeks": 24,
   "url": "https://pubmed.ncbi.nlm.nih.gov/2024983/"
  },
  {
   "trial": "Randhawa 2015 (PMID 25738849)",
   "arm": "0.1% stabilized retinol",
   "outcome": "mottled pigmentation improvement",
   "value_pct": 84,
   "n": null,
   "duration_weeks": 52,
   "url": "https://pubmed.ncbi.nlm.nih.gov/25738849/"
  }
 ]
}